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Sponsored by: Honors Program
Seminars: Wiring up the Retina
Start Date/Time: 10/16/2017 4:00 PM
End Date/Time: 10/16/2017 5:00 PM
Location: Alumni Hall B
Description: The retina is about as complicated as any other part of the vertebrate central nervous system, but its accessibility makes it especially suitable for elucidating mechanisms that govern neural circuit assembly and function. Visual information is passed from retinal photoreceptors to interneurons to retinal ganglion cells (RGCs) and then on to the rest of the brain. In mouse, each of >40 RGC types responds to specific visual features, depending on which of the >70 types of interneurons synapse on it. The first part of the lecture will take direction-selective, RGCs as an example, describing some recognition molecules that underlie assembly of the circuitry that generates their responses. Generalizing this approach to other cell types, to the rest of the brain, and to primates will require a complete cell atlas and a full inventory of the recognition molecules that each cell type expressed. The second part will summarize progress in a single-cell transcriptomic approach aimed at addressing these challenges.
Contact: Josephine Markiewicz
Phone: 263-3815
Email: Josephine.Markiewicz@nyumc.org
Speaker: Joshua R. Sanes, PhD
Speaker Institution: Harvard University
Speaker Institution Location: Cambridge, MA
Speaker Position: J.C.Tarr Professor of Molecular and Cellular Biology
Addtl. Info: Paul J. Finnegan Family Director, Center for Brain Science
Seminar Host: Ruth Lehmann
Refreshments: No
Fee Required: No
Fee Amount:
 

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